New Zinc Treatment ‘Can Help to Restore Lost Hearing’ in Mice–University Research Shows
Anyone who has ever been to a loud concert knows the feeling of ringing ears. Some people experience temporary or even permanent hearing loss or drastic changes in their perception of sound after the loud noises stop.
Scientists have discovered the biological mechanism of hearing loss caused by loud noise, which helped them find a way to prevent it.
When exposed to loud noises some people experience temporary or even permanent hearing loss or drastic changes in their perception of sound after the loud noises stop.
Researchers from the University of Pittsburgh in the US have now discovered that this noise-induced hearing loss stems from cellular damage in the inner ear that is associated with the excess of free-floating zinc, a mineral that is essential for proper cellular function and hearing.
Their experiments showed drugs that work as molecular sponges trapping excess zinc can help restore lost hearing, or if administered before an expected loud sound exposure, can protect from hearing loss.
“Noise-induced hearing loss can be debilitating. Some people start hearing sounds that aren’t there, developing a condition called tinnitus, which severely affects a person’s quality of life,” said Professor Thanos Tzounopoulos from the Pittsburgh Hearing Research Center.
“Noise-induced hearing loss impairs millions of lives but, because the biology of hearing loss is not fully understood, preventing hearing loss has been an ongoing challenge.”
To get their results, published in the journal Proceedings of the National Academy of Sciences, the team studied the inner ear cells of mice.
A CURE FOR HEREDITARY DEAFNESS: 11-Year-Old Moroccan Boy Hears for the First Time Thanks to Experimental Gene Therapy in Philadelphia
They found that hours after mice are exposed to loud noise, their inner ear zinc level spikes which, ultimately, leads to cellular damage and disrupts normal cell-to-cell communication.
Thankfully, mice who were treated with a slow-releasing compound that trapped excess free zinc were less prone to hearing loss and were protected from noise-induced damage.
MORE HEARING-LOSS STORIES: Researchers Discover Proteins That Could Soon Restore Damaged Hearing and Irreversible Deafness
This opens the door for a possible solution to the problem and lays the groundwork for the development of effective and minimally invasive treatments, and even products to protect concertgoers and musicians, in the future.
The researchers hope to test this treatment further with the goal of eventually making it available as a simple, over-the-counter option to protect oneself from hearing loss.
SHARE This Incredibly Simple Method For Potentially Controlling Hearing Los…
>read more at © GoodNews
Views: 5